Scientists have named the best time of day for vaccination

The activity of the human immune system changes depending on the time of day, scientists from the University of Geneva (UNIGE) in Switzerland and the Ludwig Maximilian University (LMU) in Germany concluded. Their study drew the attention of the publication "Science First Hand", established by the Siberian Branch of the Russian Academy of Sciences.

Scientists conducted an experiment on laboratory mice and human cell cultures, during which they monitored dendritic cells that actively recognize antigens - specific fragments of pathogens. Dendritic cells, after recognition, migrate to the lymphatic vessels, through which they reach the lymph nodes. There they "present" the detected antigen to other immune cells - T-lymphocytes, which leads to the production of antibodies.

Immunologists have come to the conclusion that dendritic cells move most actively at the end of the body's resting stage, before resuming activity. For mice it is daytime, and for humans it is early morning. Scientists believe that the time of day should be taken into account when vaccinating and during antitumor immunotherapy, as this can increase the effectiveness of the procedures.

In September, scientists from Rockefeller University concluded that vaccination after recovery from COVID-19 leads to the formation of "flexible" antibodies in the body, which allows you to get "superhuman" immunity.