Experts evaluate plasma transfusion in the treatment of critically ill COVID

Information about the uselessness of transfusion of plasma from recovered COVID-19 in the treatment of patients with the virus is erroneous, this method is one of the most effective. This was announced to RBC by the director of the Research Institute of Epidemiology and Microbiology named after G. P. Somov of Rospotrebnadzor Mikhail Shchelkanov.

A day earlier, an international team of researchers published an article in the Journal of the American Medical Association, in which they pointed out the futility of transfusion of blood plasma from survivors of coronavirus infection in the treatment of sick patients with COVID-19, including those in critical condition.

“I think that is absolutely not true. The fact is that the treatment with serum of people who have been ill, who have antibodies for all viral infections, is quite an effective method, and for some it is even very effective. I think that the problem is simply in the inability to correctly use this method in specific cases, ”said Shchelkanov.

According to him, today there are many types of clinical course and each type of clinical course requires its own algorithm for the implementation of any therapeutic approach, “including serotherapy (treatment of infections with sera -)”. “And this understanding, apparently, has not yet been formed, and until it is formed, any method will be ineffective,” he explained.

The expert believes that the method of plasma transfusion is most effective in the initial stages of treatment, and in a critical condition "it would be wrong to rely only on this method." “Nevertheless, according to the experience of other viral infections, it is at the initial stage that the so-called passive immunization, when antibodies are already delivered as part of plasma serum, is most effective,” he concluded.

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Professor of the Department of Hospital Therapy, Russian National Research Medical University. N. I. Pirogov, Alexander Karabinenko, in turn, told RBC that the process of transfusing donor plasma to patients looks very controversial. “It is believed that there are antibodies in this plasma and they can promote recovery, but clinical experience shows that this may or may not help. And in most cases, this really does not help <...> Apparently, what scientists were counting on does not work yet, ”he said.

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According to him, today in the world there are no single guidelines for the management of patients with COVID-19 infection, nor methods for their treatment. “The Ministry of Health is already preparing the 13th revision of clinical recommendations, but there are still no established methods of treatment. They were released in September, but I think these recommendations are not perfect yet,” he added.

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Treatment of patients with coronavirus with blood plasma with antibodies in Russia began in April 2020. The fact that this method is effective for the treatment of patients with COVID-19 was said by both official authorities and specialists. The United States later began to treat coronavirus-infected patients with this method .

Earlier, Moscow Mayor Sergei Sobyanin signed a decree according to which 696.3 million rubles will be allocated for the procurement and processing of plasma for the treatment of patients with coronavirus. Of these, 510.8 million will go to the procurement, processing and storage of donated blood. RUB 97.3 million will spend on the processing of plasma and the production of the Covid-globulin drug from it, which the Ministry of Health registered in April this year. Another 88.2 million rubles. will spend on payments to blood donors with antibodies to the coronavirus.

Over the previous day, 25,133 new cases of COVID-19 infection were detected in Russia, another 929 people died - this is a new record for daily mortality in Russia. The previous record was set on October 5, when 895 people were declared dead from the coronavirus.

How the number of deaths from Covid-19 in Russia is changing Daily data from the operational headquarters Source: federal and regional emergency headquarters for combating coronavirus Data for Russia i