The Federal State Budgetary Institution "All-Russian Research Institute of Animal Health" has received a patent for the invention of a kit for detecting the genome of the pathogen causing contagious bovine pleuropneumonia using the PCR method.

A document certifying the exclusive right and authorship of specialists from the Federal Center for Animal HEALTH has been issued for the "Test system for detecting DNA of the causative agent of contagious bovine pleuropneumonia using the polymerase chain reaction method in real time."

Contagious bovine pleuropneumonia ( CBPP) is a highly contagious respiratory disease of ruminants (cattle, zebu, yaks, and buffalo) caused by the bacterium Mycoplasma mycoides subsp. mycoides SC (Mmm SC). The disease has a significant impact on global livestock production due to its potential for rapid spread, high mortality and morbidity, and exclusion from international live animal trade. it is subject to mandatory notification to the Organization for Animal Health (OIE). Since 2019, RUSSIA has had official international status as free from CBPP.

To date, Russia lacked domestically produced RT-PCR test systems that detect M. mycoides subsp. Mycoides SC (Mmm SC) DNA. Therefore, the development of modern molecular diagnostic methods used to prevent the introduction of the pathogen when cattle are imported into the Russian Federation was an urgent task.

The state-of-the-art test system of the All-Russian Research Institute of Animal Health (ARRIAH) based on real-time polymerase chain reaction (RT-PCR) demonstrates high sensitivity and specificity for the detected agent. Drawing on unique practical experience and expert knowledge accumulated over years of work, the ARRIAH continues to improve and offer new products designed to address pressing issues in animal disease diagnostics.

The patent granted for the invention enables the Federal State Budgetary Institution "All-Russian Research Institute of Animal Health" to produce and sell diagnostic kits for the DNA detection of the bovine TB pathogen using real-time polymerase chain reaction (PCR) on the domestic market. This patent makes it possible to diagnose such a particularly dangerous disease as bovine TB, including when monitoring imported cattle entering the Russian Federation.