Brain cancer suppressed with a sugary substance from beans and meat

Scientists hope that soon this substance can be used to combat one of the most aggressive forms of brain cancer - medulloblastoma.

British biologists have slowed down the growth rate of medulloblastoma with the help of SUGAR IP6. it deprived cancer cells of access to critical nutrients. The results of the study were published in the scientific journal Nature Communications.

“We hardly knew how the G4 subtype of medulloblastoma develops, despite the fact that this is its most common form. We have identified a mechanism that allows her cancer cells to grow uncontrollably, and also found a way to block this growth. This gives hope for the creation of new methods of combating aggressive forms of brain cancer in children,” said one of the authors of the study, Silvia Marino, a professor at Queen Mary University of London.

A detailed study showed that the cells of this tumor are vulnerable to IP6, a sugary substance that plant and animal cells produce to store phosphorus reserves. This substance is found in large quantities in cereals, beans and MEAT.

Further experiments showed that a small amount of IP6 dramatically slowed down the growth rate of tumor cells, and also made them vulnerable to the popular anti-cancer drug cisplatin. After learning about this, the scientists tested how the combination of these two drugs would affect the survival of mice implanted with medulloblastoma cell cultures.

The results of the experiments, according to British researchers, give great hope that IP6 can be widely used in the near future to combat medulloblastoma in clinical practice. In addition, scientists suggest that the substance will similarly affect other types of cancerous tumors with similar changes in the activity of the BMI1 gene.