New method enables faster development of African swine fever vaccines
Photo is illustrative in nature. From open sources.
According to the developers, the new system will help researchers develop vaccines and study the pathogenesis and biology of the highly contagious ASF virus .
This reverse genetics system allows scientists to rapidly generate genetically modified versions of the ASF virus. Its applicability has the potential to significantly reduce economic losses caused by ASF and also provides much-needed solutions for containing the virus's spread.
Using a reverse genetics approach against ASF will not only help us better understand the mechanism of action of this virus, but will also create opportunities applicable to other emerging viruses such as Zika, Chikungunya, Mayaro and Ebola, which have caused large outbreaks and pose a serious threat to global HEALTH.
Reverse genetics allows scientists to quickly create genetically modified versions of ASF. First, synthetic DNA is created—a laboratory-made version of the virus's genetic material. Parts of the virus are modified and then assembled into complete genes.
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