
Among the drugs on the market, there are two drugs that can block the coronavirus infection. This conclusion was made by researchers from the University of Tampere. According to Yle, during experiments on human cells, it was found that the combination of bafetinib and a staurosporine derivative (UCN-01) prevents cell inflammation. In addition, these drugs enhance the effect of each other, scientists believe. According to them, these drugs, when used together, are effective against the original form of COVID-19 and the Delta strain.
The study, published in the journal Briefings in Bioinformatics, hosted scientists from the University of Helsinki, Aarhus University in Denmark, the University of Queensland in Australia, and Eötvös Loránd University in Hungary.
Note that this is not the first remedy for COVID-19 reported by Finnish experts. A week ago, Finnish virologists announced the creation of a nasal spray that prevents coronavirus infection (SARS-CoV-2) from entering the human body. Currently, experts are trying to understand whether the remedy is effective in post-exposure prophylaxis.
Explaining the principle of the spray, the researchers recall that viruses enter human cells with the help of spike-like spike proteins located on their surface. Coronaviruses have a weak point in these proteins. The scientists found a molecule called TriSb92 that compresses or binds the protein's trident-like spike and prevents it from entering cells. Therefore, the virus that gets on the mucous membranes does not cause disease.
According to the researchers, TriSb92 protected laboratory mice from coronavirus for eight hours. Under similar conditions, all mice that did not receive a spray with a molecule became infected with covid.